The clashes will kick off with a Basque derby where Deportivo Alavés will look to change their dynamic. The Vitoria-based side is in 15th position with 7 points, one point away from safety. Andrea Esteban's team has gone five consecutive matches without a win, earning just 1 point from the last 15 available. “It's a very special match. We're really looking forward to playing at Mendizorroza,” declared Elene Viles, who previously played for the San Sebastián-based side. Laia Parera will be the only absentee for the home team due to suspension. Meanwhile, Real Sociedad, who are 12th in the standings with 9 points, come into the fixture in excellent form, having gone five consecutive matches unbeaten across all competitions, including a 2-0 victory against Fenerbahçe in the first leg of the Europa Cup round of 16. The only two absentees for the San Sebastián club for this fixture will be Aiara Agirrezabala and Paula Fernández, who are injured.

The Palamós stadium will host the Catalan derby. FC Badalona Women are in 14th position with 8 points, just one point above the relegation zone. Marc Ballester's side has gone five consecutive matches without a win, with two draws and three defeats. Antonia Canales, with a cruciate ligament injury, Berta Pujadas, Izarne Sarasola, Vicky Losada, and Lauri Requena will be the home side's absentees for the match. Opposing them will be FC Barcelona, leaders of the domestic competition with 21 points, who arrive after a 0-8 victory against Køge in the Champions League. The absentees for the culé team will be Irene Paredes, Laia Aleixandri, with a cruciate ligament injury, and Vicky López. Last season, both teams met four times, with three victories for the azulgranas and a 0-0 draw in the first leg of the Copa de la Reina semi-finals. A result the home side will be looking to repeat.